IL-4 蛋白
Quick Overview for IL-4 蛋白 (ABIN2830786)
抗原
See all IL-4 (IL4) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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序列
- HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS
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产品特性
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/mL, corresponding to a specific activity of > 1.0 x 106 IU/mg.
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过滤
- 0.2 μm filtered
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 2 x PBS, pH 7.4, 5 % trehalose
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储存条件
- -20 °C
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- IL-4 (IL4) (Interleukin 4 (IL4))
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别名
- IL4
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背景
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Relevance: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity). {ECO:0000250}.
Synonyms: IL-4, BSF-1, Lymphocyte stimulatory factor 1 -
分子量
- 14.9 kDa
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UniProt
- P51492
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
抗原
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