Indian Hedgehog Protein (IHH)
Quick Overview for Indian Hedgehog Protein (IHH) (ABIN2830462)
抗原
See all Indian Hedgehog (IHH) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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序列
- IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG
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产品特性
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.
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过滤
- 0.2 μm filtered
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Indian Hedgehog (IHH) (AA 28-202) protein (His tag)
IHH 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Indian Hedgehog (IHH) (AA 29-202) protein (His tag)IHH 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Indian Hedgehog (IHH) (AA 203-411) protein (His tag)IHH 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 20 mM PB, pH 7.4, 150 mM NaCl
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储存条件
- -20 °C
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- Indian Hedgehog (IHH)
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别名
- IHH
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背景
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Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
Synonyms: IHH, -
分子量
- 19.8 kDa
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UniProt
- Q14623
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途径
- Hedgehog Signaling
抗原
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