Pleiotrophin Protein (PTN)
Quick Overview for Pleiotrophin Protein (PTN) (ABIN2830304)
抗原
See all Pleiotrophin (PTN) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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序列
- GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
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产品特性
- Biological Activity: Fully biologically active when compared to standard. The biological activity was measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons, when neurons were plated on 96 well culture plates that had been pre-coated wi
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过滤
- 0.2 μm filtered
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Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)
PTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Pleiotrophin (PTN) protein (His tag)PTN 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Pleiotrophin (PTN) (AA 1-168) protein (GST tag)PTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pleiotrophin (PTN) (Active) proteinPTN 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)PTN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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- Pleiotrophin (PTN)
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别名
- PTN
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背景
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Relevance: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. {ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:1768439}.
Synonyms: PTN, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule -
分子量
- 15.3 kDa
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UniProt
- P21246
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途径
- RTK signaling
抗原
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