Nerve Growth Factor Protein (NGF) (AA 122-241)
This Recombinant Nerve Growth Factor protein is expressed in Mammalian Cells.
Quick Overview for Nerve Growth Factor Protein (NGF) (AA 122-241) (ABIN2830300)
抗原
See all Nerve Growth Factor (NGF) 蛋白
Nerve Growth Factor (NGF)
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
Mammalian Cells
应用范围
Functional Studies (Func)
纯度
>90 % as determined by SDS-PAGE.
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产品特性
- AA 122-241
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序列
- Ser122-Ala241, Accession # CAA36832
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产品特性
- Biological Activity: The ED50, as determined by a cell proliferation assay using human TF-1 cells, is less than 2 ng/mL.
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过滤
- 0.2 μm filtered
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Nerve Growth Factor (NGF) (AA 122-239) protein (His tag)
NGF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.2 % acetic acid
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储存条件
- -20 °C
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- Nerve Growth Factor (NGF)
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别名
- NGF
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背景
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Relevance: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}.
Synonyms: Beta-NGF, -
分子量
- 13.5 kDa
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UniProt
- P01138
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途径
- Regulation of Cell Size
抗原
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