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VEGFA 蛋白

VEGFA 宿主: 小鼠 宿主: Insect cells (Sf9) Recombinant >95 % (SDS-PAGE) SDS Active
产品编号 ABIN2746007
发货至: 中国
  • 抗原 See all VEGFA 蛋白
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 18
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    小鼠
    资源
    • 35
    • 16
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    • 4
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    • 1
    Insect cells (Sf9)
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    小鼠
    产品特性
    Mouse VEGF 164 (164aa).
    纯度
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product VEGFA 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    The ED50 for stimulation of cell proliferation by human umbilical vein endothelial cells for VEGF 164 has been determined to be in the range of 1-5ng/ml.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with 50 mM acetic acid to a concentration not lower than 50 μg/mL.
    浓度
    Lot specific
    缓冲液
    Lyophilized.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    别名
    VEGF 164 (VEGFA 产品)
    别名
    MVCD1 Protein, VEGF Protein, VPF Protein, Vegf Protein, Vegf120 Protein, Vegf164 Protein, Vegf188 Protein, Vpf Protein, vegf Protein, vegfa Protein, wu:fj82c06 Protein, VEGF-A Protein, VEGF164 Protein, eVEGF120 Protein, eVEGF164 Protein, vegf-a Protein, vpf Protein, vefg Protein, si:dkey-14d8.3 Protein, wu:fd42e02 Protein, vascular endothelial growth factor A Protein, vascular endothelial growth factor Aa Protein, vascular endothelial growth factor A L homeolog Protein, vascular endothelial growth factor Ab Protein, VEGFA Protein, Vegfa Protein, vegfaa Protein, vegfa.L Protein, vegfa Protein, vegfab Protein
    背景
    Mouse vascular endothelial growth factor 164 (VEGF 164) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemoattractant for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.
    分子量
    ~48kDa
    UniProt
    Q00731
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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