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FGF2 Protein (AA 131-288)

FGF2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % (SDS-PAGE) SDS
产品编号 ABIN2745670
发货至: 中国
  • 抗原 See all FGF2 蛋白
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    蛋白类型
    Recombinant
    产品特性
    AA 131-288
    宿主
    • 19
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 36
    • 9
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    产品特性
    Human FGF-2 (aa 131-288) is untagged.
    纯度
    >95 % (SDS-PAGE)
    内毒素水平
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product FGF2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with 100 μL sterile water.
    浓度
    Lot specific
    缓冲液
    Lyophilized. Contains PBS + 0.1 mM DTT.
    储存液
    Dithiothreitol (DTT)
    注意事项
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    别名
    FGF-2 (FGF2 产品)
    别名
    BFGF Protein, FGF-2 Protein, FGFB Protein, HBGF-2 Protein, Fgf-2 Protein, Fgfb Protein, bFGF Protein, fibroblast growth factor 2 Protein, fibroblast growth factor 2 (basic) Protein, FGF2 Protein, Fgf2 Protein, fgf2 Protein
    背景
    FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signaling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
    分子量
    18 kDa
    UniProt
    P09038
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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