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FGF1 Protein (AA 16-155)

FGF1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % (SDS-PAGE) SDS
产品编号 ABIN2745666
发货至: 中国
  • 抗原 See all FGF1 蛋白
    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
    蛋白类型
    Recombinant
    产品特性
    AA 16-155
    宿主
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 27
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    原理
    FGF-1 (human) (rec.) (untagged)
    交叉反应
    产品特性
    Human FGF-1 (aa 16-155) is untagged.
    纯度
    >95 % (SDS-PAGE)
    内毒素水平
    <0.01EU/μg purified protein (LAL test).
    Top Product
    Discover our top product FGF1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with 100 μL sterile water.
    浓度
    0.1 mg/mL
    缓冲液
    In PBS containing 0.2 mM DTT.
    注意事项
    After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
    储存条件
    4 °C,-20 °C
    储存方法

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

    有效期
    6 months
  • 抗原
    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
    别名
    FGF-1 (FGF1 产品)
    背景

    Fibroblast Growth Factor 1, Acidic Fibroblast Growth Factor, Endothelial Cell Growth Factor, ECGF, Heparin-binding Growth Factor 1, HBGF-1

    Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic, ECGF, HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.

    分子量
    ~16kDa
    UniProt
    P05230
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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