Quick Overview for TIE1 蛋白 (ABIN2733707)
抗原
See all TIE1 蛋白
TIE1
(tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
应用范围
Antibody Production (AbP), Standard (STD)
纯度
> 95 % as determined by SDS-PAGE and Coomassie blue staining
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产品特性
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- Recombinant human TIE1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
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缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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别名
- Tie1
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背景
- This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 81 kDa
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NCBI登录号
- NP_005415
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途径
- RTK signaling
抗原
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