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Quick Overview for SCARB2 蛋白 (ABIN2731449)
抗原
See all SCARB2 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
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- Recombinant human SCARB2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
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Scavenger Receptor Class B, Member 2 (SCARB2) protein (His tag)
SCARB2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Scavenger Receptor Class B, Member 2 (SCARB2) protein (Fc Tag)SCARB2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Scavenger Receptor Class B, Member 2 (SCARB2) (AA 1-478) protein (GST tag)SCARB2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
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缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
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别名
- Scarb2
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背景
- The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
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分子量
- 47.6 kDa
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NCBI登录号
- NP_005497
抗原
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