PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
Quick Overview for PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2730237)
抗原
See all PC 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 3
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标记
- This PC protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Pyruvic carboxylase (PC) (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PC (Pyruvate Carboxylase (PC))
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别名
- Pyruvic Carboxylase (Pc)
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背景
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
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分子量
- 127.3 kDa
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NCBI登录号
- NP_001035806
抗原
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