Leptin Protein (LEP) (Myc-DYKDDDDK Tag)
Quick Overview for Leptin Protein (LEP) (Myc-DYKDDDDK Tag) (ABIN2724653)
抗原
See all Leptin (LEP) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This Leptin protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Leptin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Leptin (LEP)
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别名
- Leptin
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背景
- This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
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分子量
- 16 kDa
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NCBI登录号
- NP_000221
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途径
- JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
抗原
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