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Leptin Protein (LEP) (Myc-DYKDDDDK Tag)

This Recombinant Leptin protein is expressed in HEK-293 Cells.
产品编号 ABIN2724653
发货至: 中国

Quick Overview for Leptin Protein (LEP) (Myc-DYKDDDDK Tag) (ABIN2724653)

抗原

See all Leptin (LEP) 蛋白
Leptin (LEP)

蛋白类型

Recombinant

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资源

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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This Leptin protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human Leptin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    Leptin (LEP)

    别名

    Leptin

    背景

    This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

    分子量

    16 kDa

    NCBI登录号

    NP_000221

    途径

    JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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