KLHL3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for KLHL3 Protein (Myc-DYKDDDDK Tag) (ABIN2724309)
抗原
See all KLHL3 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This KLHL3 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human KLHL3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Kelch-Like 3 (KLHL3) (AA 1-587) protein (His tag)
custom-made KLHL3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Kelch-Like 3 (KLHL3) (AA 1-587) protein (His tag)custom-made KLHL3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Kelch-Like 3 (KLHL3) (AA 1-301) protein (GST tag)KLHL3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KLHL3 (Kelch-Like 3 (KLHL3))
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别名
- Klhl3
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背景
- This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D) a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 64.8 kDa
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NCBI登录号
- NP_059111
抗原
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