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IL-4 Protein (Transcript Variant 1)

This Recombinant IL-4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2723719
发货至: 中国

Quick Overview for IL-4 Protein (Transcript Variant 1) (ABIN2723719)

抗原

See all IL-4 (IL4) 蛋白
IL-4 (IL4) (Interleukin 4 (IL4))

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

应用范围

Standard (STD), Antibody Production (AbP)

纯度

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 1

    产品特性

    • Recombinant human Interleukin-4 / IL4 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone

    内毒素水平

    < 0.1 EU per μg protein as determined by LAL test
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    限制

    仅限研究用
  • 缓冲液

    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    Interleukin-4,il4

    背景

    The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    分子量

    15.1 kDa

    NCBI登录号

    NP_000580

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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