IL-4 Protein (Transcript Variant 1)
Quick Overview for IL-4 Protein (Transcript Variant 1) (ABIN2723719)
抗原
See all IL-4 (IL4) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 1
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产品特性
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- Recombinant human Interleukin-4 / IL4 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
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缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL-4 (IL4) (Interleukin 4 (IL4))
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别名
- Interleukin-4,il4
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背景
- The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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分子量
- 15.1 kDa
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NCBI登录号
- NP_000580
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
抗原
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