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IL-10 Protein (Myc-DYKDDDDK Tag)

This Recombinant IL-10 protein is expressed in HEK-293 Cells.
产品编号 ABIN2723581
发货至: 中国

Quick Overview for IL-10 Protein (Myc-DYKDDDDK Tag) (ABIN2723581)

抗原

See all IL-10 (IL10) 蛋白
IL-10 (IL10) (Interleukin 10 (IL10))

蛋白类型

Recombinant

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HEK-293 Cells

应用范围

Standard (STD), Antibody Production (AbP)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This IL-10 protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human Interleukin-10 / IL10 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    Interleukin-10,il10

    背景

    The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

    分子量

    18.6 kDa

    NCBI登录号

    NP_000563

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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