GFRA1 Protein (Transcript Variant 3)
Our Local Distributor
北京 101111
Quick Overview for GFRA1 Protein (Transcript Variant 3) (ABIN2721853)
抗原
See all GFRA1 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
产品特性
- Transcript Variant 3
-
产品特性
-
- Recombinant human GFRA1 / GDNFR-alpha (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
-
-
-
-
应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
-
-
-
缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
-
别名
- Gfra1,gdnfr-alpha
-
背景
- This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
-
分子量
- 46.3 kDa
-
NCBI登录号
- NP_001138925
抗原
-