Doublecortin Protein (DCX) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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Quick Overview for Doublecortin Protein (DCX) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2719682)
抗原
See all Doublecortin (DCX) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 2
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标记
- This Doublecortin protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Doublecortin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Doublecortin (DCX) (AA 1-365) protein (His tag)
custom-made DCX 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Doublecortin (DCX) (AA 1-366) protein (His tag)custom-made DCX 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Doublecortin (DCX) (AA 1-360) protein (GST tag)DCX 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Doublecortin (DCX) (AA 107-208) protein (His-IF2DI Tag)DCX 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Doublecortin (DCX)
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别名
- Doublecortin
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背景
- This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 40.4 kDa
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NCBI登录号
- NP_835365
抗原
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