BCL2L1 Protein (Transcript Variant 2)
Quick Overview for BCL2L1 Protein (Transcript Variant 2) (ABIN2715193)
抗原
See all BCL2L1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 2
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产品特性
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- Recombinant human Bcl-2-like 1 (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
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BCL2-Like 1 (BCL2L1) (AA 1-233) protein (His tag)
custom-made BCL2L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (His tag)custom-made BCL2L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2-Like 1 (BCL2L1) (AA 1-209) protein (His tag)BCL2L1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-212) protein (His tag)BCL2L1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
BCL2-Like 1 (BCL2L1) (AA 1-233) protein (GST tag)BCL2L1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BCL2-Like 1 (BCL2L1) (AA 1-212) protein (Fc Tag)BCL2L1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
BCL2-Like 1 (BCL2L1) (AA 1-212) (Active) protein (His tag)BCL2L1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE Active
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 20 mM HEPES, 50 mM KCl, 20 % Glycerol, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- Bcl-2-Like 1
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背景
- The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
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分子量
- 24.8 kDa
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NCBI登录号
- NP_001182
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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