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CD3 Protein (CD3) (His tag)

CD3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713619
发货至: 中国
  • 抗原 See all CD3 蛋白
    CD3
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    HEK-293 Cells
    标记
    This CD3 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CD3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Top Product
    Discover our top product CD3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    别名
    CD3 Protein, AI504783 Protein, CD3epsilon Protein, T3e Protein, cd3-gamma Protein, cd3g Protein, cd3g-a Protein, cd3g/d Protein, cd3gd Protein, t3g Protein, CD3e molecule Protein, CD3d molecule Protein, CD3 antigen, epsilon polypeptide Protein, CD3g molecule S homeolog Protein, CD3E Protein, CD3D Protein, Cd3e Protein, cd3g.S Protein
    背景
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
    分子量
    12.79kD
    NCBI登录号
    NP_000724
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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