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CD3 Protein (CD3) (Myc-DYKDDDDK Tag)

CD3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713617
发货至: 中国
  • 抗原 See all CD3 蛋白
    CD3
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    HEK-293 Cells
    标记
    This CD3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CD3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    别名
    CD3 Protein, AI504783 Protein, CD3epsilon Protein, T3e Protein, cd3-gamma Protein, cd3g Protein, cd3g-a Protein, cd3g/d Protein, cd3gd Protein, t3g Protein, CD3e molecule Protein, CD3d molecule Protein, CD3 antigen, epsilon polypeptide Protein, CD3g molecule S homeolog Protein, CD3E Protein, CD3D Protein, Cd3e Protein, cd3g.S Protein
    背景
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
    分子量
    20.7 kDa
    NCBI登录号
    NP_000724
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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