CBFB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
-
- 抗原 See all CBFB 蛋白
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This CBFB protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human CBFB (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CBFB 蛋白
-
Want other Options for this Protein
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at 106,314.67 ¥Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at 164,706.05 ¥Your project requires further customization? Contact us and discover our custom protein solutions
-
Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) protein (His tag)
custom-made CBFB 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Core-Binding Factor, beta Subunit (CBFB) (AA 1-187) protein (His tag)custom-made CBFB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) protein (GST tag)CBFB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- 别名
- Cbfb (CBFB 产品)
- 背景
- The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 21.3 kDa
- NCBI登录号
- NP_001746
- 途径
- Regulation of Lipid Metabolism by PPARalpha
-
