Caspase 3 Protein (CASP3) (Myc-DYKDDDDK Tag)
Quick Overview for Caspase 3 Protein (CASP3) (Myc-DYKDDDDK Tag) (ABIN2713205)
抗原
See all Caspase 3 (CASP3) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This Caspase 3 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Caspase-3 (transcript variant beta) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Caspase 3 (CASP3) (AA 29-277) protein (His-IF2DI Tag)
CASP3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Caspase 3 (CASP3) (AA 1-277) protein (GST tag)CASP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 3 (CASP3) (AA 176-277) proteinCASP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80% by SDS-PAGE SDS
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Caspase 3 (CASP3)
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别名
- Caspase-3
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背景
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
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分子量
- 31.4 kDa
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NCBI登录号
- NP_116786
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
抗原
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