Patched 1 Protein (PTCH1) (DYKDDDDK Tag)
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- 抗原 See all Patched 1 (PTCH1) 蛋白
- Patched 1 (PTCH1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Insect cells (Sf9)
- 标记
- This Patched 1 protein is labelled with DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PTCH1 (C-term DDK tag, transcript variant 1b) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTCH1 蛋白
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Patched 1 (PTCH1) (AA 1-1447) protein (His tag)
custom-made PTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Patched 1 (PTCH1) (AA 1-1434) protein (His tag)custom-made PTCH1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Patched 1 (PTCH1) (AA 841-940) protein (GST tag)PTCH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Patched 1 (PTCH1) proteinPTCH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Patched 1 (PTCH1)
- 别名
- Ptch1 (PTCH1 产品)
- 背景
- This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
- 分子量
- 30.4 kDa
- NCBI登录号
- NP_000255
- 途径
- Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
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