TAF1 Protein (AA 1522-1656) (His tag,DYKDDDDK Tag)
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Quick Overview for TAF1 Protein (AA 1522-1656) (His tag,DYKDDDDK Tag) (ABIN2669687)
抗原
See all TAF1 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 1522-1656
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标记
- This TAF1 protein is labelled with His tag,DYKDDDDK Tag.
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产品特性
- The peptide corresponding to amino acids 1522-1656 that contains the bromodomain sequences of TAF1 (accession number NP_004597.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 21.75 kDa. It shows binding specificity for acetylated H3K14.
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TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1400-1518) protein (His-IF2DI Tag)
TAF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1519-1651) protein (His-IF2DI Tag)TAF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) (AA 1400-1651) protein (His-IF2DI Tag)TAF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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应用备注
- Recombinant TAF1 (1522-1656) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
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限制
- 仅限研究用
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注意事项
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))
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别名
- TAF1
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背景
- TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor (TAF1) is the largest component and core scaffold of the TFIID basal transcription factor complex. TAF1 contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. TAF1 also contains bromodomains for interaction with other proteins. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. TAF1 has been shown to phosphorylate threonine 55 of p53 which leads to MDM2-mediated degradation of p53. TAF1 also phosphorylates GTF2A1 and GTF2F1 on serine residues. In addition, TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle.
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分子量
- 21.75 kDa
抗原
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