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FGF9 Protein (AA 3-208)

This Recombinant FGF9 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2667403
发货至: 中国
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Quick Overview for FGF9 Protein (AA 3-208) (ABIN2667403)

抗原

See all FGF9 (FGF-9) 蛋白
FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Flow Cytometry (FACS)

纯度

>95 % , as determined by Coomassie stained SDS-PAGE gel and HLPC analysis.
  • 产品特性

    AA 3-208

    内毒素水平

    Less than 0.1 ng per μg of protein.

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Biological activity: ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106 units/mg, as measured by its ability to stimulate thymidine uptake by BaF3 cells expressing FGF receptors in a dose dependent manner.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For maximum results, quick spin vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. It is recommended to further dilute in a buffer, such as 5 % Trehalose, and store working aliquots at -20 °C to -80 °C.

    缓冲液

    Lyophilized, carrier-free.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Unopened vial can be stored at -20°C or -70°C.
  • 抗原

    FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))

    别名

    FGF-9

    背景

    FGF-9 is a heparin-binding growth factor belonging to the fibroblast growth factor (FGF) family. FGF-9 was first identified as a secretory protein from the human glioma cell line NMC-G1 and is reported to be widely expressed in rat brain. In the central nervous system, FGF-9 acts as an autocrine and a paracrine growth factor that is required for the development, growth, and survival of neuronal cells. During prenatal stages, FGF-9 expression is crucial for normal lung and airway development. FGF-9 null mutant mice show the phenotype of severe lung hypoplasia, which results in perinatal death. FGF-9 is key in stimulating cell proliferation after arterial, skeletal, and hepatic injuries. FGF-9 is also involved in tumorgenesis, enhancing transformation and progression of several malignant diseases, including prostate, lung, and colon cancer.

    分子量

    The 206 amino acid recombinant protein has a predicted molecular mass of approximately 23.2 kDa. The predicted N-terminal amino acid is Pro.
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