FGF9 Protein (AA 3-208)
Quick Overview for FGF9 Protein (AA 3-208) (ABIN2667403)
抗原
See all FGF9 (FGF-9) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 3-208
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内毒素水平
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Less than 0.1 ng per μg of protein.
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Biological activity: ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106 units/mg, as measured by its ability to stimulate thymidine uptake by BaF3 cells expressing FGF receptors in a dose dependent manner.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For maximum results, quick spin vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. It is recommended to further dilute in a buffer, such as 5 % Trehalose, and store working aliquots at -20 °C to -80 °C.
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缓冲液
- Lyophilized, carrier-free.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Unopened vial can be stored at -20°C or -70°C.
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- FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))
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别名
- FGF-9
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背景
- FGF-9 is a heparin-binding growth factor belonging to the fibroblast growth factor (FGF) family. FGF-9 was first identified as a secretory protein from the human glioma cell line NMC-G1 and is reported to be widely expressed in rat brain. In the central nervous system, FGF-9 acts as an autocrine and a paracrine growth factor that is required for the development, growth, and survival of neuronal cells. During prenatal stages, FGF-9 expression is crucial for normal lung and airway development. FGF-9 null mutant mice show the phenotype of severe lung hypoplasia, which results in perinatal death. FGF-9 is key in stimulating cell proliferation after arterial, skeletal, and hepatic injuries. FGF-9 is also involved in tumorgenesis, enhancing transformation and progression of several malignant diseases, including prostate, lung, and colon cancer.
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分子量
- The 206 amino acid recombinant protein has a predicted molecular mass of approximately 23.2 kDa. The predicted N-terminal amino acid is Pro.
抗原
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