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FGF10 Protein (AA 40-208, N-Term)

FGF10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % , as determined by Coomassie stained SDS-PAGE gel and HLPC analysis. FACS Active
产品编号 ABIN2667400
发货至: 中国
  • 抗原 See all FGF10 蛋白
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 40-208, N-Term
    宿主
    • 11
    • 4
    • 3
    资源
    • 15
    • 2
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Flow Cytometry (FACS)
    纯度
    >95 % , as determined by Coomassie stained SDS-PAGE gel and HLPC analysis.
    内毒素水平

    Less than 0.1 ng per μg of protein.

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    Discover our top product FGF10 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Biological activity: ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106 units/mg, as measured by its ability to stimulate thymidine uptake by BaF3 cells expressing FGF receptors in a dose dependent manner.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    For maximum results, quick spin vial prior to opening. Reconstitute in 5 mM sodium phosphate, pH 8.0 to a concentration of <0.5 mg/mL. It is recommended to further dilute in a buffer, such as 5 % Trehalose, and store working aliquots at -20 °C to -80 °C.
    缓冲液
    Lyophilized, carrier-free.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Unopened vial can be stored at -20°C or -70°C.
  • 抗原
    FGF10 (Fibroblast Growth Factor 10 (FGF10))
    别名
    FGF-10 (FGF10 产品)
    别名
    fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein
    背景
    FGF-10, also named keratinocyte growth factor 2 (KGF-2), is a member of the fibroblast growth factor (FGF) family and is functionally similar to the other FGF family member FGF-7. FGF-10 acts as a paracrine growth factor and plays an important role in embryonic development, cell growth, and cell differentiation. During embryonic stages, FGF-10 is essential for lung development, promoting lung morphogenesis, branching, and airway extension. FGF-10 was revealed to participate in wound healing, promoting growth of epithelial cells in normal and wounded tissue. Increased expression of FGF-10 and the receptor FGFR2-IIIb has been reported to associate with various malignant diseases, such as prostate, breast, pancreas, and colorectum cancer, suggesting the role of FGF-10 in carcinogenesis.
    分子量
    The 170 amino acid recombinant protein has a predicted molecular mass of approximately 19.3 kDa. The predicted N-terminal amino acid is Met.
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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