FGF10 Protein (AA 40-208, N-Term)
Quick Overview for FGF10 Protein (AA 40-208, N-Term) (ABIN2667400)
抗原
See all FGF10 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 40-208, N-Term
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内毒素水平
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Less than 0.1 ng per μg of protein.
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Fibroblast Growth Factor 10 (FGF10) (AA 38-208) protein (Biotin)
FGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 10 (FGF10) (AA 38-208) proteinFGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by Tris-Bis PAGE
Fibroblast Growth Factor 10 (FGF10) (AA 38-137) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) (AA 37-215) protein (His tag)FGF10 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 10 (FGF10) (AA 1-208) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Biological activity: ED50 ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106 units/mg, as measured by its ability to stimulate thymidine uptake by BaF3 cells expressing FGF receptors in a dose dependent manner.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For maximum results, quick spin vial prior to opening. Reconstitute in 5 mM sodium phosphate, pH 8.0 to a concentration of <0.5 mg/mL. It is recommended to further dilute in a buffer, such as 5 % Trehalose, and store working aliquots at -20 °C to -80 °C.
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缓冲液
- Lyophilized, carrier-free.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Unopened vial can be stored at -20°C or -70°C.
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- FGF10 (Fibroblast Growth Factor 10 (FGF10))
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别名
- FGF-10
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背景
- FGF-10, also named keratinocyte growth factor 2 (KGF-2), is a member of the fibroblast growth factor (FGF) family and is functionally similar to the other FGF family member FGF-7. FGF-10 acts as a paracrine growth factor and plays an important role in embryonic development, cell growth, and cell differentiation. During embryonic stages, FGF-10 is essential for lung development, promoting lung morphogenesis, branching, and airway extension. FGF-10 was revealed to participate in wound healing, promoting growth of epithelial cells in normal and wounded tissue. Increased expression of FGF-10 and the receptor FGFR2-IIIb has been reported to associate with various malignant diseases, such as prostate, breast, pancreas, and colorectum cancer, suggesting the role of FGF-10 in carcinogenesis.
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分子量
- The 170 amino acid recombinant protein has a predicted molecular mass of approximately 19.3 kDa. The predicted N-terminal amino acid is Met.
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
抗原
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