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PD-L1 Protein (Twin-Strep tag)

This Recombinant PD-L1 protein is expressed in HEK-293 Cells.
产品编号 ABIN2566857
发货至: 中国
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Quick Overview for PD-L1 Protein (Twin-Strep tag) (ABIN2566857)

抗原

See all PD-L1 蛋白
PD-L1 (CD274 (PD-L1))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

应用范围

Western Blotting (WB)

纯度

>95 % as determined by SDS-PAGE.
  • 标记

    This PD-L1 protein is labelled with Twin-Strep tag.

    产品特性

    Fusion tag: C-Twin Strep Tag

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  • 应用备注

    This recombinant protein can be used for WB. For research use only.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -80 °C,-20 °C

    储存方法

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    PDL1

    背景

    Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 involve in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

    分子量

    28.2 kDa

    基因ID

    29126

    NCBI登录号

    NP_054862

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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