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CD58 Protein (CD58) (His tag)

This Recombinant CD58 protein is expressed in HEK-293 Cells.
产品编号 ABIN2566429
发货至: 中国

Quick Overview for CD58 Protein (CD58) (His tag) (ABIN2566429)

抗原

See all CD58 蛋白
CD58

蛋白类型

Recombinant

生物活性

Active

宿主

资源

  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

应用范围

Western Blotting (WB)

纯度

>95 % as determined by SDS-PAGE.
  • 标记

    This CD58 protein is labelled with His tag.

    产品特性

    Measured in a cell proliferation assay using human CD3+ T cells in the presence of anti-CD3. The ED50 for this effect is typically 1 - 5 μg/mL in the presence of anti-CD3 immobilized at 25 ng/mL.

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  • 应用备注

    This recombinant protein can be used for WB. For research use only.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -80 °C,-20 °C

    储存方法

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD58

    别名

    CD58

    背景

    CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

    分子量

    22.3 kDa

    基因ID

    965

    UniProt

    P19256
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