CD58 Protein (CD58) (His tag)
Quick Overview for CD58 Protein (CD58) (His tag) (ABIN2566429)
抗原
See all CD58 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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标记
- This CD58 protein is labelled with His tag.
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产品特性
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Measured in a cell proliferation assay using human CD3+ T cells in the presence of anti-CD3. The ED50 for this effect is typically 1 - 5 μg/mL in the presence of anti-CD3 immobilized at 25 ng/mL.
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应用备注
- This recombinant protein can be used for WB. For research use only.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -80 °C,-20 °C
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储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- CD58
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别名
- CD58
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背景
- CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
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分子量
- 22.3 kDa
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基因ID
- 965
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UniProt
- P19256
抗原
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