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VEGFB 蛋白

This Recombinant VEGFB protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2469198
发货至: 中国

Quick Overview for VEGFB 蛋白 (ABIN2469198)

抗原

See all VEGFB 蛋白
VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

< 98 % by SDS-PAGE gel and HPLC analyses.
  • 序列

    PVSQPDAPGH QRKVVSWIDV YTRATCQPRE VVVPLTVELM GTVAKQLVPS CVTVQRCGGC CPDDGLECVP TGQHQVRMQI LMIRYPSSQL GEMSLEEHSQ CECRPKKKDS AVKPDSPRPL CPRCTQHHQR PDPRTCRCRC RRRSFLRCQG RGLELNPDTC RCRKLRR

    内毒素水平

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    注意事项

    As with any protein, exposing VEGF-B recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -20 °C

    储存方法

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted VEGF-B is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    有效期

    24 months
  • 抗原

    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

    别名

    VEGF-B

    背景

    VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a "cysteine knot like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant human VEGF-B is a 38.0 kDa disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.

    基因ID

    7423

    NCBI登录号

    NP_001230662

    OMIM

    344179103

    UniProt

    P49765

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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