CD70 Protein (Soluble)
Quick Overview for CD70 Protein (Soluble) (ABIN2469031)
抗原
See all CD70 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- Soluble
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序列
- HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P
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产品特性
- Biological activity was determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/mL. Note: Results may vary with PBMC donors.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 136,947.45 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing sCD27 Ligand recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted sCD27 Ligand stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- CD70 (CD70 Molecule (CD70))
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别名
- CD27 Ligand
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背景
- CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. ProSci s recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
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基因ID
- 970
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NCBI登录号
- NP_001243
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OMIM
- 4507605
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
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