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CD70 Protein (Soluble)

This Recombinant CD70 protein is expressed in CHO Cells.
产品编号 ABIN2469031
发货至: 中国

Quick Overview for CD70 Protein (Soluble) (ABIN2469031)

抗原

See all CD70 蛋白
CD70 (CD70 Molecule (CD70))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 32
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资源

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CHO Cells

纯度

< 95 % by SDS-PAGE gel and HPLC analyses.
  • 产品特性

    Soluble

    序列

    HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P

    产品特性

    Biological activity was determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/mL. Note: Results may vary with PBMC donors.

    内毒素水平

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 136,947.45 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    注意事项

    As with any protein, exposing sCD27 Ligand recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -20 °C

    储存方法

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted sCD27 Ligand stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    有效期

    24 months
  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD27 Ligand

    背景

    CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. ProSci s recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.

    基因ID

    970

    NCBI登录号

    NP_001243

    OMIM

    4507605

    UniProt

    P32970

    途径

    Cancer Immune Checkpoints
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