Midkine 蛋白
Quick Overview for Midkine 蛋白 (ABIN2468825)
抗原
See all Midkine (MDK) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MVAKKKEKVK KGSECSEWTW GPCTPSSKDC GMGFREGTCG AQTQRVHCKV PCNWKKEFGA DCKYKFESWG ACDGSTGTKA RQGTLKKARY NAQCQETIRV TKPCTSKTKS KTKAKKGKGK D
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产品特性
- Biological activity was determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/mL.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Midkine (Neurite Growth-Promoting Factor 2) (MDK) (Active) protein
MDK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-140) protein (His tag)MDK 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His-Avi Tag)MDK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-140) protein (His-IF2DI Tag)MDK 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 1-143) protein (GST tag)MDK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His tag)MDK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (Fc Tag)MDK 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-143) protein (Fc Tag)MDK 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing Midkine recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Midkine stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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别名
- Midkine
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背景
- Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.4 kDa protein containing 121 amino acid residues including five intra-molecular disulfide bonds.
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基因ID
- 17242
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NCBI登录号
- NP_001012335
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OMIM
- 59894790
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UniProt
- P12025
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途径
- RTK signaling, M Phase, Skeletal Muscle Fiber Development
抗原
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