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Leptin Protein (LEP)

This Recombinant Leptin protein is expressed in 大肠杆菌（E. Coli）.

产品编号 ABIN2468757

发货至: 中国

Quick Overview for Leptin Protein (LEP) (ABIN2468757)

抗原

See all Leptin (LEP) 蛋白

Leptin (LEP)

蛋白类型

Recombinant

生物活性

Active

宿主

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小鼠

资源

大肠杆菌（E. Coli）

纯度

< 98 % by SDS-PAGE gel and HPLC analyses.

Discover our top product LEP 蛋白

序列

MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC

产品特性

Murine Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 μg Leptin/gm of body weight for 14 days. Significant effects on body weight , food consumption, and plasma glucose levels were observed to saline - treated controls

内毒素水平

Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Leptin (LEP) (AA 22-167) protein (Fc Tag)
LEP 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Leptin (LEP) protein
LEP 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE.

Leptin (LEP) protein (His tag)
LEP 宿主: Goldfish 宿主: 酵母菌 Recombinant > 95 % as determined by reducing SDS-PAGE.

Leptin (LEP) (AA 22-167) protein (His tag)
LEP 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Leptin (LEP) (AA 22-167) protein (His tag)
LEP 宿主: Pig 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Leptin (LEP) (AA 22-167) protein (His-IF2DI Tag)
LEP 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Leptin (LEP) (AA 428-635) protein (His-IF2DI Tag)
LEP 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Leptin (LEP) (AA 22-167) protein (GST tag)
LEP 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

Leptin (LEP) (AA 22-167) protein (Fc Tag)
LEP 宿主: 人宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Leptin (LEP) protein
LEP 宿主: 大鼠宿主: 大肠杆菌（E. Coli） Recombinant 95,00% SDS

限制

仅限研究用
状态

Lyophilized

注意事项

As with any protein, exposing Leptin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

储存条件

-20 °C

储存方法

The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Leptin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

有效期

24 months
抗原

Leptin (LEP)

别名

Leptin

背景

Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant murine Leptin is a 16.2 kDa protein containing 147 amino acid residues.

基因ID

16846

NCBI登录号

NP_032519

OMIM

6678678

UniProt

P41160

途径

JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process

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