IL-34 蛋白
This Recombinant IL-34 protein is expressed in HEK-293 Cells.
Quick Overview for IL-34 蛋白 (ABIN2468681)
抗原
See all IL-34 (IL34) 蛋白
IL-34 (IL34)
(Interleukin 34 (IL34))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
HEK-293 Cells
纯度
< 95 % by SDS-PAGE gel and HPLC analyses.
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序列
- NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
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产品特性
- Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing IL-34 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-34 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- IL-34 (IL34) (Interleukin 34 (IL34))
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别名
- IL-34
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背景
- IL-34 is a homodimeric cytokine that is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.
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基因ID
- 146433
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NCBI登录号
- NP_001166242
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OMIM
- 289666750
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UniProt
- Q6ZMJ4
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途径
- RTK signaling
抗原
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