IL-24 蛋白
Quick Overview for IL-24 蛋白 (ABIN2468661)
抗原
See all IL-24 (IL24) 蛋白蛋白类型
宿主
资源
纯度
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序列
- QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
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Interleukin 24 (IL24) (AA 51-206) (Active) protein (His tag)
IL24 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Interleukin 24 (IL24) (AA 58-167) protein (GST tag)IL24 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-206) protein (GST tag)IL24 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-207) protein (GST tag)IL24 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- IL-24 (IL24) (Interleukin 24 (IL24))
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别名
- IL-24
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背景
- IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
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基因ID
- 11009
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NCBI登录号
- NP_001172085
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OMIM
- 297632401
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UniProt
- Q13007
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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