Betacellulin Protein (BTC)
Quick Overview for Betacellulin Protein (BTC) (ABIN2468275)
抗原
See all Betacellulin (BTC) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY
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产品特性
- Biological activity was determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expected ED50 is < 0.01 ng/mL, corresponding to a specific activity of > 1 x 108 units/mg.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 1-178) protein (GST tag)BTC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-111) protein (Fc Tag)BTC 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing Betacellulin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Betacellulin stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- Betacellulin (BTC)
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别名
- Betacellulin
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背景
- Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
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基因ID
- 12223
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NCBI登录号
- NP_031594
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OMIM
- 6680812
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UniProt
- Q05928
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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