Quick Overview for FGF acidic (AA 16-155) 蛋白 (ABIN2180569)
抗原
FGF acidic
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
>98 % as determined by SDS-PAGE.
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产品特性
- AA 16-155
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序列
- AA 16-155
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产品特性
- This protein carries no "tag". The protein has a calculated MW of 15.8 kDa. The protein migrates as 15.8 kDa under reducing (R) condition (SDS-PAGE).
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- FGF acidic
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背景
- Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.
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分子量
- 16.0 kDa
抗原
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