Interferon gamma Protein (IFNG)
(1 reference)Quick Overview for Interferon gamma Protein (IFNG) (ABIN935525)
抗原
See all Interferon gamma (IFNG) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
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产品特性
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Purified recombinant Mouse IFN gamma protein
Expression System: E.coli
Bioactivity: Determined by its ability to inhibit the proliferation of Mouse WEHI-279 cells. The expected ED50 is ? 0.2 ng/mL, corresponding to a specific activity of ? 5 x 10^6 units/mg. -
内毒素水平
- < 0.1 ng per μg (1 EU/μg).
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Interferon gamma (IFNG) (AA 24-161) protein (His-Avi Tag)
IFNG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interferon gamma (IFNG) (AA 24-161) protein (His-Avi Tag,Biotin)IFNG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interferon gamma (IFNG) (Active) proteinIFNG 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interferon gamma (IFNG) (AA 23-155) (Active) proteinIFNG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by reducing SDS-PAGE. Active
Interferon gamma (IFNG) proteinIFNG 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma (IFNG) (AA 1-144) protein (His tag)IFNG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interferon gamma (IFNG) (AA 24-174) protein (His tag)IFNG 宿主: Hamster 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interferon gamma (IFNG) (AA 24-166) protein (His tag)IFNG 宿主: Pig 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interferon gamma (IFNG) (Active) protein (Fc Tag)IFNG 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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说明
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Biological activity: Determined by its ability to inhibit the proliferation of Mouse WEHI-279 cells. The expected ED50 is approx. 0.2 ng/mL, corresponding to a specific activity of approx. 5 x 10^6 units/mg.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 5-10 M Sodium Phosphate, pH 8.0 to a concentration of 1.0 mg/mL.
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缓冲液
- Lyophilized from 10 mM Na3PO4, pH 7.0, with 20 mM NaCl.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- RT/-20 °C
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: "New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis." in: Biochemistry, Vol. 1, pp. 128-31 (PubMed).
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: "New ribonucleic acid species associated wihin the formation of the photosynthetic apparatus in Euglena gracilis." in: Biochemistry, Vol. 1, pp. 128-31 (PubMed).
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- Interferon gamma (IFNG)
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别名
- IFN gamma
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背景
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IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.
Alternative Names: Interferon gamma protein, T cell interferon protein, IFN-g protein, type II interferon protein, IFN g protein, MAF protein, Immune Interferon protein -
分子量
- 15.6 kDa
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途径
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
抗原
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