NRG1-beta 1 Protein (AA 176-246)
NRG1-beta 1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by reducing SDS-PAGE.
-
- 抗原 See all NRG1-beta 1 products
- NRG1-beta 1 (Neuregulin-1 beta 1 (NRG1-beta 1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 176-246
- 宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Pro-Neuregulin-1/NRG1-β1/HRG1-β1 (Thr176-Lys246)
- 序列
- TSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNYV MASFYKHLGI EFMEAEELYQ K
- 产品特性
- Recombinant Human Pro-neuregulin-1 is produced by our E. coli expression system. The target protein is expressed with sequence (Thr176-Lys246) of Human NRG1.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
-
Neuregulin-1 beta 1 (NRG1-beta 1) (AA 2-246) (Active) protein (Fc Tag)
NRG1-beta 1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- NRG1-beta 1 (Neuregulin-1 beta 1 (NRG1-beta 1))
- Abstract
- NRG1-beta 1 产品
- 背景
-
Neuregulin-1 (heregulin-1,NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.
Synonyms: Pro-neuregulin-1,Neuregulin-1 beta 1,NRG1-beta 1,HRG1-beta 1, EGF,NRG1, GGF, HGL, HRGA, NDF, SMDF, - 分子量
- 8.2 kDa
-
You are here:
