FGF1 Protein (AA 2-155)
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- 抗原 See all FGF1 蛋白
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-155
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Fibroblast Growth Factor 1/FGF-1/FGFa (Ala2-Asp155)
- 序列
- AEGEITTFTA LTEKFNLPPG NYKKPKLLYC SNGGHFLRIL PDGTVDGTRD RSDQHIQLQL SAESVGEVYI KSTETGQYLA MDTDGLLYGS QTPNEECLFL ERLEENHYNT YISKKHAEKN WFVGLKKNGS CKRGPRTHYG QKAILFLPLP VSSD
- 产品特性
- Recombinant Human Fibroblast growth factor 1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Asp155) of Human FGF1 fused with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FGF1 蛋白
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Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) (Active) protein (His tag)
FGF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 1-155) (Active) protein (His tag,GST tag)FGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (Active) proteinFGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (Active) proteinFGF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) protein (His tag)FGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) protein (His tag)FGF1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 1-155) protein (GST tag)FGF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) protein (GST tag)FGF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
- 别名
- Fibroblast Growth Factor 1 (FGF1 产品)
- 别名
- AFGF Protein, ECGF Protein, ECGF-beta Protein, ECGFA Protein, ECGFB Protein, FGF-1 Protein, FGF-alpha Protein, FGFA Protein, GLIO703 Protein, HBGF-1 Protein, HBGF1 Protein, Fgf1 Protein, FGF1 Protein, aFGF Protein, ecgf Protein, fgfa Protein, ecgfa Protein, ecgfb Protein, fgf-1 Protein, hbgf1 Protein, glio703 Protein, ecgf-beta Protein, fgf-alpha Protein, Dffrx Protein, Fam Protein, Fgf-1 Protein, Fgfa Protein, zgc:136885 Protein, LOC100221393 Protein, fgf1 Protein, zgc:73249 Protein, fibroblast growth factor 1 Protein, fibroblast growth factor 1 L homeolog Protein, fibroblast growth factor 1b Protein, fibroblast growth factor 1a Protein, FGF1 Protein, fgf1.L Protein, fgf1 Protein, Fgf1 Protein, fgf1b Protein, LOC100221393 Protein, fgf1a Protein
- 背景
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FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
Synonyms: Fibroblast Growth Factor 1, FGF-1, Acidic Fibroblast Growth Factor, aFGF, Endothelial Cell Growth Factor, ECGF Heparin-Binding Growth Factor 1, HBGF-1, FGF1, FGFA - 分子量
- 31.6 kDa
- UniProt
- P05230
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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