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VEGFC Protein (AA 102-227)

This Recombinant VEGFC protein is expressed in HEK-293T Cells.
产品编号 ABIN2018451
发货至: 中国

Quick Overview for VEGFC Protein (AA 102-227) (ABIN2018451)

抗原

See all VEGFC 蛋白
VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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HEK-293T Cells

纯度

> 95 % as analyzed by SDS-PAGE.
  • 产品特性

    AA 102-227

    产品特性

    Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. The ED50 for this effect is < 0.5 μg/mL.
    AA 102-227 with an N-terminal Met.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Human Vascular Endothelial Growth Factor C remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Vascular Endothelial Growth Factor C should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.

    有效期

    6 months
  • 抗原

    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

    别名

    Vascular Endothelial Growth Factor C (VEGF-C)

    背景

    Vascular endothelial growth factor C (VEGF-C) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. VEGF-C is expressed in various tissues, however it is not produced in peripheral blood lymphocytes. It forms cell surface-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. The structure and function of VEGF-C is similar to those of vascular endothelial growth factor D (VEGF-D).Recombinant human VEGF-C produced in HEK293 cells is a polypeptide chain containing 126 amino acids. A fully biologically active molecule, rhVEGF-C has a molecular mass of 16-19 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Flt4 ligand, VRP

    分子量

    16-19 kDa, observed by reducing SDS-PAGE.

    UniProt

    P14844

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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