TFF3 蛋白
Our Local Distributor
北京 101111
Quick Overview for TFF3 蛋白 (ABIN2018418)
抗原
See all TFF3 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF
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产品特性
- Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 μg/mL, corresponding to a specific activity of > 100 IU/mg.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1 EU/μg of rHuTFF3 as determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
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缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))
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别名
- Trefoil Factor 3(TFF3)
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背景
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The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.
Synonyms: Trefoil Factor 3 Human, TFF3 Human -
分子量
- 6.6 kDa, a single non-glycosylated polypeptide chain containing 59 amino acids, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
抗原
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