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TFF3 蛋白

This Recombinant TFF3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2018418
发货至: 中国

Quick Overview for TFF3 蛋白 (ABIN2018418)

抗原

See all TFF3 蛋白
TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE and HPLC analyses.
  • 序列

    EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF

    产品特性

    Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 μg/mL, corresponding to a specific activity of > 100 IU/mg.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1 EU/μg of rHuTFF3 as determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

    缓冲液

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
  • 抗原

    TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

    别名

    Trefoil Factor 3(TFF3)

    背景

    The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.
    Synonyms: Trefoil Factor 3 Human, TFF3 Human

    分子量

    6.6 kDa, a single non-glycosylated polypeptide chain containing 59 amino acids, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
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