PDGFD Protein (AA 250-370)
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- 抗原 See all PDGFD 蛋白
- PDGFD (Platelet Derived Growth Factor D (PDGFD))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 250-370
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宿主
- 人
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资源
- CHO Cells
- 产品特性
- ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product PDGFD 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- PDGFD (Platelet Derived Growth Factor D (PDGFD))
- Abstract
- PDGFD 产品
- 别名
- IEGF Protein, SCDGF-B Protein, SCDGFB Protein, Scdgfb Protein, rSCDGF-B Protein, PDGFD Protein, 1110003I09Rik Protein, platelet derived growth factor D Protein, platelet-derived growth factor, D polypeptide Protein, PDGFD Protein, Pdgfd Protein
- 背景
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PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB - 分子量
- 19-21 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q9GZP0
- 途径
- RTK signaling, Platelet-derived growth Factor Receptor Signaling
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