PDGFD Protein (AA 250-370)
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北京 101111
Quick Overview for PDGFD Protein (AA 250-370) (ABIN2018314)
抗原
See all PDGFD 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 250-370
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产品特性
- ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- PDGFD (Platelet Derived Growth Factor D (PDGFD))
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背景
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PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB -
分子量
- 19-21 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q9GZP0
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途径
- RTK signaling, Platelet-derived growth Factor Receptor Signaling
抗原
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