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PDGFD Protein (AA 250-370)

This Recombinant PDGFD protein is expressed in CHO Cells.
产品编号 ABIN2018314
发货至: 中国

Quick Overview for PDGFD Protein (AA 250-370) (ABIN2018314)

抗原

See all PDGFD 蛋白
PDGFD (Platelet Derived Growth Factor D (PDGFD))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 9
  • 2
  • 2

资源

  • 6
  • 3
  • 2
  • 1
  • 1
CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE.
  • 产品特性

    AA 250-370

    产品特性

    ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    PDGFD (Platelet Derived Growth Factor D (PDGFD))

    背景

    PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
    Synonyms: platelet-derived growth factor D, IEGF, SCDGFB

    分子量

    19-21 kDa, observed by reducing SDS-PAGE.

    UniProt

    Q9GZP0

    途径

    RTK signaling, Platelet-derived growth Factor Receptor Signaling
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