Oncostatin M Protein (OSM) (AA 24-206)
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- 抗原 See all Oncostatin M (OSM) 蛋白
- Oncostatin M (OSM)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-206
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宿主
- 小鼠
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资源
- HEK-293T Cells
- 产品特性
- ED50 < 0.4 ng/mL, measured in a cell proliferation assay using NIH-3T3 cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product OSM 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Murine Oncostatin-M remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Oncostatin-M should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- Oncostatin M (OSM)
- 别名
- Oncostatin-M (OSM) (OSM 产品)
- 背景
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Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi's sarcoma cells. OSM signals through two types of receptors, one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial.
Synonyms: OSM - 分子量
- 10-40 kDa, observed by reducing SDS-PAGE.
- UniProt
- P53347
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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