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Oncostatin M Protein (OSM) (AA 24-206)

OSM 宿主: 小鼠 宿主: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018305
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 蛋白
    Oncostatin M (OSM)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-206
    宿主
    • 25
    • 5
    • 4
    • 3
    • 1
    • 1
    小鼠
    资源
    • 20
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293T Cells
    产品特性
    ED50 < 0.4 ng/mL, measured in a cell proliferation assay using NIH-3T3 cells.
    纯度
    > 95 % as analyzed by SDS-PAGE and HPLC.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product OSM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Murine Oncostatin-M remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Oncostatin-M should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    Oncostatin M (OSM)
    别名
    Oncostatin-M (OSM) (OSM 产品)
    背景
    Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi's sarcoma cells. OSM signals through two types of receptors, one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial.
    Synonyms: OSM
    分子量
    10-40 kDa, observed by reducing SDS-PAGE.
    UniProt
    P53347
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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