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Oncostatin M Protein (OSM) (AA 24-206)

This anti-Oncostatin M antibody (ABIN2018306) is a HEK-293T Cells antibody detecting Oncostatin M in . Suitable for Mouse.
产品编号 ABIN2018306
发货至: 中国

Quick Overview for Oncostatin M Protein (OSM) (AA 24-206) (ABIN2018306)

抗原

See all Oncostatin M (OSM) 蛋白
Oncostatin M (OSM)

蛋白类型

Recombinant

生物活性

Active

宿主

  • 26
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小鼠

资源

  • 20
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HEK-293T Cells

纯度

> 95 % as analyzed by SDS-PAGE and HPLC.
  • 产品特性

    AA 24-206

    产品特性

    ED50 < 0.4 ng/mL, measured in a cell proliferation assay using NIH-3T3 cells.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Murine Oncostatin-M remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Oncostatin-M should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    Oncostatin M (OSM)

    别名

    Oncostatin-M (OSM)

    背景

    Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi's sarcoma cells. OSM signals through two types of receptors, one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial.
    Synonyms: OSM

    分子量

    10-40 kDa, observed by reducing SDS-PAGE.

    UniProt

    P53347

    途径

    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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