FGF7 Protein (AA 32-194)
Quick Overview for FGF7 Protein (AA 32-194) (ABIN2018174)
抗原
See all FGF7 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 32-194
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产品特性
- ED50 < 2 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0x 10^5 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Fibroblast Growth Factor 7 (FGF7) (Active) protein
FGF7 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag)FGF7 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag,Biotin)FGF7 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 7 (FGF7) protein (His tag)FGF7 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Fibroblast Growth Factor 7 (FGF7) (AA 32-194) protein (His tag)FGF7 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 7 (FGF7) (AA 1-97) protein (GST tag)FGF7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant mouse Keratinocyte Growth Factor (rmKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmKGF remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
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有效期
- 6 months
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- FGF7 (Fibroblast Growth Factor 7 (FGF7))
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别名
- Keratinocyte Growth Factor (KGF)
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背景
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Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF's roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands., KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney. Recombinant mouse Keratinocyte Growth Factor (rmKGF) produced in E. coli is a single non-glycosylated polypeptide chain containing 163 amino acids. A fully biologically active molecule, rmKGF has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-7, HBGF-7 -
分子量
- 18.7 kDa, observed by reducing SDS-PAGE.
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UniProt
- P36363
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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