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FGF7 Protein (AA 32-194)

FGF7 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN2018176
发货至: 中国
  • 抗原 See all FGF7 蛋白
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 32-194
    宿主
    • 20
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    小鼠
    资源
    • 18
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 < 2 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0x 10^5 units/mg.
    纯度
    > 95 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant mouse Keratinocyte Growth Factor (rmKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmKGF remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    别名
    Keratinocyte Growth Factor (KGF) (FGF7 产品)
    别名
    HBGF-7 Protein, KGF Protein, Kgf Protein, kgf Protein, FGF-7 Protein, fgf7 Protein, fibroblast growth factor 7 Protein, fibroblast growth factor 7 L homeolog Protein, FGF7 Protein, Fgf7 Protein, fgf7 Protein, fgf7.L Protein
    背景
    Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF's roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands., KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney. Recombinant mouse Keratinocyte Growth Factor (rmKGF) produced in E. coli is a single non-glycosylated polypeptide chain containing 163 amino acids. A fully biologically active molecule, rmKGF has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Fibroblast Growth Factor-7, HBGF-7
    分子量
    18.7 kDa, observed by reducing SDS-PAGE.
    UniProt
    P36363
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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