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CXCL10 蛋白

This Recombinant CXCL10 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2018167
发货至: 中国

Quick Overview for CXCL10 蛋白 (ABIN2018167)

抗原

See all CXCL10 蛋白
CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

蛋白类型

Recombinant

生物活性

Active

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小鼠

资源

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大肠杆菌(E. Coli)

纯度

> 97 % by SDS-PAGE and HPLC analyses.
  • 序列

    IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP

    产品特性

    Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1-10.0 ng/mL in the presence of IL-2.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1 EU/μg of rMuIP-10/CXCL10 as determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

    缓冲液

    Lyophilized from a 0.2 μm filtered concentrated solution in 2 x PBS, pH 7.4.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
  • 抗原

    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

    别名

    IP10/CXCL10

    背景

    Gamma-Interferon Inducible Protein 10 (IP-10)/CXCL10 was originally identified as an IFN-gamma-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1beta, TNF-alpha, IL-12 and viruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of skin. The mouse homologue of human IP-10, Crg-2, has been cloned andshown to share approximately 67 % amino acid sequence identity with human IP-10.
    Synonyms: gamma-Interferon Inducible Protein-10, CXCL10, crg-2

    分子量

    8.7 kDa, a single non-glycosylated polypeptide chain containing 77 amino acids.
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