IL-10 Protein (AA 19-178)
Quick Overview for IL-10 Protein (AA 19-178) (ABIN2018048)
抗原
See all IL-10 (IL10) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 19-178
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产品特性
- ED50 <8 μg /mL, measured in a bioassay using C6 cells.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 10 (IL10) (AA 19-178) protein
IL10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 (IL10) (AA 19-178) protein (His-Avi Tag)IL10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 (IL10) (AA 19-178) protein (His-Avi Tag,Biotin)IL10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 10 (IL10) (AA 19-178) (Active) proteinIL10 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 10 (IL10) (Active) proteinIL10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 10 (IL10) (AA 22-178) protein (His tag)IL10 宿主: Hamster 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 10 (IL10) (AA 1-178) protein (GST tag)IL10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 10 (IL10) proteinIL10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interleukin 10 (IL10) (AA 19-178) protein (His tag)IL10 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant rat Interleukin-10(IL-10) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-10 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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有效期
- 6 months
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- IL-10 (IL10) (Interleukin 10 (IL10))
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别名
- Interleukin-10 (IL-10)
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背景
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Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80 % sequence homology with the Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells. It also displays the ability to suppress Antigen-Presenting Cell (APC) function. The net effect of Interleukin-10 appears to be inhibitory, however, stimulatory effects, such as stimulation of B cell maturation and antibody production, are also reported.
Synonyms: B-TCGF, CSIF, TGIF -
分子量
- 8-22 kDa, observed by reducing SDS-PAGE.
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UniProt
- P29456
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
抗原
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