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FGF2 Protein (AA 10-155)

FGF2 宿主: Cow 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE analysis. Active
产品编号 ABIN2017858
发货至: 中国
  • 抗原 See all FGF2 蛋白
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 10-155
    宿主
    • 25
    • 10
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cow
    资源
    • 39
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 < 1.0 ng/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 1 x 10^6 units/mg.
    纯度
    > 95 % by SDS-PAGE analysis.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant bovine Fibroblast Growth Factor-basic (rbFGF-basic) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rbFGF-basic remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    别名
    Fibroblast Growth Factor-Basic (FGF-Basic) (FGF2 产品)
    别名
    BFGF Protein, FGF-2 Protein, FGFB Protein, HBGF-2 Protein, Fgf-2 Protein, Fgfb Protein, bFGF Protein, fibroblast growth factor 2 Protein, fibroblast growth factor 2 (basic) Protein, FGF2 Protein, Fgf2 Protein, fgf2 Protein
    背景
    Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the beta trefoil structure. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.Recombinant bovine Fibroblast Growth Factor-basic (rbFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rbFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE.
    Synonyms: FGF-2, BFGF, FGFB, HBGF-2
    分子量
    16.4 kDa, observed by reducing SDS-PAGE.
    UniProt
    P03969
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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